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The test measures the porphyrin derivative kryptopyrrol (Mauve factor) in urine.
Kryptopyrrol is a porphyrin derivative. Porphyrins are cyclic compounds that readily bind metal ions. They constitute haeme-proteins, including haemoglobin, myoglobin and cytochrome P450. Inherited or occasionally acquired defect in haeme-synthesis can result in accumulation and increased excretion of porphyrins or porphyrin precursors. Clinical manifestations may be neurovisceral and/or cutaneous.
The condition of pyrroluria is associated with a deficiency of vitamin B6 (pyridoxine) and zinc.
- Anorexia
- Anemia that does not repond to iron
- Alcoholism
- Autonomic dysfunction
- Chemical exposure
- Cutaneous photosensitivity
- Hyperactivity
- Heavy metal poisoning (lead)
- Menstrual irregularities
- Neuropsychiatric symptoms
- Schizophrenia
- Stress (prolonged)
- Malformation of knee cartilage along with joint pains
- Abdominal pain
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